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Igualmente en la gingivitis estreptocócica, causada por el estreptococo beta-hemolítico del grupo A (Streptococcus pyogenes) y que se presenta como complicación de una faringoamigdalitis estreptocócica aguda, en la que se deben utilizar antibióticos activos frente a este microorganismo (19). En el caso de la GUN, aparte del tratamiento antibiótico, es recomendable el desbridamiento con irrigación abundante (16). La aplicación tópica de enjuagues bucales con clorhexidina o suero salino resulta eficaz para controlar el dolor y la ulceración en este proceso. El tratamiento antimicrobiano no es la única terapia frente a la infección odontogénica, ya que en muchos casos la administración exclusiva de antibióticos no es suficiente para erradicar dicha infección. Dependiendo de las características del proceso y del paciente, el tratamiento óptimo de una determinada infección podría requerir antimicrobianos sistémicos o locales, tratamiento odontológico o cirugía, o bien la combinacion de varios de ellos (6,16,17). No deben administrarse tetraciclinas (excepto doxiciclina, minociclina y tigeciclina) a pacientes con insuficiencia renal previa, ya que pueden producir insuficiencia renal.

La forma de administración depende de las instrucciones dadas por el medicamento a disolver o diluir. El medicamento debe reconstituirse o diluirse inmediatamente antes de su uso. Si está embarazada o en periodo de lactancia, cree que podría estar embarazada o tiene intención de quedarse embarazada, consulte a su médico o farmacéutico antes de utilizar este medicamento. El Agua para preparaciones inyectables B.Braun es agua estéril para preparaciones inyectables.

Frecuentemente muestra resistencia a un gran número de antimicrobianos, y en ocasiones, tan sólo muestra actividad frente a colimicina y tigeciclina. Por esto, el tratamiento con tigeciclina se promovió casi como el tratamiento de elección en estas infecciones. Desgraciadamente, la CMI90 de los Acinetobacter baumanii frecuentemente supera, o está en el límite, de lo que su perfil farmacodinámico indica una actuación antimicrobiana eficaz.

Debido a su toxicidad y elevada resistencia su uso actualmente es muy escaso. El metronidazol es el principal componente de la familia de los 5-nitroimidazoles. Es un antibiótico con gran actividad bactericida frente a anaerobios y algunos microaerófilos y continúa siendo muy útil en el tratamiento de infecciones bacterianas y parasitarias. También representa un tratamiento alternativo en infecciones complicadas de piel y tejidos blandos, situaciones en las que con frecuencia se encuentran implicados patógenos multirresistentes, como S. Aureus resistente a meticilina, enterococo multirresistente y enterobacterias portadoras de betalactamasas de espectro ampliado10,eleven.

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